Studies on combination chemotherapy for malignant lymphoma

Combination chemotherapy ("CHOP-Bleo") in advanced (non-Hodgkin) malignant lymphoma.

Forty-seven adults with advanced malignant lymphoma (the majority in stage IV) were treated with a combination of cyclophosphamide, hydroxyldaunorubicin (Adriamycin), vincristine (Oncovin), prednisone, and bleomycin (CHOP-Bleo). The complete remission (CR) rate was 66%. The overall response (complete + partial remission) was 92%. The CR rate in patients with diffuse histiocytic lymphoma (DHL) w...

Treatment of malignant pheochromocytoma with combination chemotherapy.

Three patients with rapidly progressive, disseminated malignant pheochromocytoma were treated with a combination chemotherapeutic regimen consisting of cyclophosphamide, vincristine, and dacarbazine in repeated 21- to 28-day cycles. All three patients had a marked decrease in blood pressure and an improvement in performance status within the first few cycles of treatment. At a follow-up of 6 to...

Chemotherapy in Ovine Malignant Theileriosis

PRIMARY MALIGNANT LYMPHOMA OF THE BREAST

A case of primary malignant non-Hodgkin's lymphoma of the breast is reported. This is the first well-documented case of breast lymphoma in our institution and also in Iran. The diagnosis of primary breast lymphoma requires the presence of lymphomatous infiltration in close ass, tissue in patients with neither previous lymphoma nor concurrent lymphoma in another site. There is no definite cl...

Pulmonary nocardiosis complicating malignant lymphoma successfully treated with chemotherapy.

A case of pulmonary nocardiosis is reported in a patient with malignant lymphoma and hypoimmunoglobuliwmia. The nocardiosis initially appeared as a dense infiltration in the right qper lobe, subsequently as bilateral long infiltrations. Nocardia asteroides was found in infralaryngeal secretion obtained by transtracheal aspiration. Treatment with sulfadine, lrimethoprim, and sulfamethoxazole (Se...